Science... sort of
Conversations about things that are science, things that are sort of science, and things that wish they were science. A member of the Brachiolope Media Network.
 

If you're interested in helping the people of West Virginia recover from some pretty horrific recent flooding, you can check out the list of options compiled by The Huffington Post

00:00:00 - Patrick and Ryan are joined by Daphne Pringle, who's a post-doctoral fellow at the Hunstman Cancer Institute of the University of Utah. She's sick of us getting epigenetics wrong like we did in episode 241, so she's here to sort us out. She uses mice to study oncogenes and tumors and cancer and all that. It's pretty far outside of our typical biology talk, so segment one is just trying to explain the basics. Here's some background reading: Raf/MEK/ERK, mouse models, and BRAF targeting

00:35:53 - Alcohol is a carcinogen probably. Oh well. Daphne represents Utah with her Uinta Detour Double IPA. Patrick was sent some cans of Elevated IPA by listener Matty J. Thanks! And Ryan classes up the joint with an Educated Guess Cabernet Sauvignon. 

00:43:21 - Now that we have totally covered the basics of Daphne's research, let's talk about her recent publication in PLOS ONE. Will Daphne and her team cure cancer? Only if they can get through the FDA's 15 year approval process! Also, if you wanted to see a Tazzy Devil joey in a pouch, here you go

01:16:43 - PaleoPOWs are a lot like the FDA approval process; only the strong survive. First up, a new recurring donation from Mark H. Thanks, Mark! Next, Peter C. has a question about population genetics that we're hoping Daphne can help us answer. It involves space travel and maybe racism? Patrick presents a Facebook post from Brennen M. who wants us to know about his favorite book about food science called Modernist Cuisine. Finally, Ryan presents the winners of the iTunes review contest calculated using random.org! The runners up: Kendh and Patrick in Des Moines. And our grand prize goes to Molec-bio! Thanks to everyone who participated. Be sure to follow Daphne on Twitter (@drpringleetal) to follow along as she saves us all. 

Thanks for listening and be sure to check out the Brachiolope Media Network for more great science podcasts!

Music used in this week's show:

Morning New Disease - Jets to Brazil
The West Virginia Hills - Moastsville String Ticklers
Waiting - Green Day

Direct download: 247_-_The_Best_Laid_Plans.mp3
Category:podcasts -- posted at: 10:41am PST

This was our first time recording since the tragic Pulse shooting in Orlando. We encourage our US listeners to share their thoughts with their elected representatives. You can find yours and their contact info here.

00:00:00 - We begin this week by talking about some literal bridge building. Because of things like physics and geology, engineers have to rethink how we build roads around bridges. Joe assumes Ryan and Abe know about soil science. He's wrong. But some researchers at the University of Texas, Arlington, have developed special giant foam blocks to help solve the bridge settling dilemma. All rivers in this segment referred to as Kwai for clarity. 

00:21:45 - Drinks, like bridges, get you where you're going. Abe pops the top off a Hop Savant from Crooked Stave. Ryan, thinking back on his afternoon at Corvus Coffee Roasters with Abe, has a Cold Brew IPA from Rogue. Joe B. bucks tradition with a Best Damn Cherry Cola, which while it may not sound like it, is actually an alcoholic beverage. It's not his first time having booze on the show, but it is rare. This leads to a discussion of choosing one's science specialty. 

00:29:31 - UPDATES. How often do you actually see follow-up reporting in science journalism? For us, it's rarely. To put our money where our mouth is here is some that. First, Abe is excited to announce that the newly discovered elements first discussed in episode 234 now have names! Next, that weird animal we talked about in episode 229 has finally found a place on the family tree of life (open access paper here), welcome to club Siphonophorae, buddy.

00:48:04 - PaleoPOWs are a lot like updates in that sometimes they really are just updates. Joe starts off complaining about vocal plosives with a new recurring donation from Pedro P. in Chile. Muchas gracias, Pedro! Ryan has an e-mail from frequent correspondent Tyler V., who corrects him about what Einstein won his Nobel prize for in episode 196. Abe finishes things up with an iTunes review, the final review from the Summer Solstice iTunes Review Challenge written by Cynthia. You can also go check out an interview with Joe on the Baja SAE Shop Talk podcast

Thanks for listening and be sure to check out the Brachiolope Media Network for more great science podcasts!

Music for this week's show:

Bridge Over Troubled Waters - Simon & Garfunkel
Campfire Kansas - The Get Up Kids
The Power of Love - Huey Lewis and the News

Direct download: 246_-_Bridging_the_Gap.mp3
Category:podcasts -- posted at: 11:20am PST